








Make Your Brain (& Body) Happy
The benefits of saffron are endless. Saffron has been used in Eastern medicine for thousands of years as a powerful antioxidant and aphrodisiac. Today, the “happiness spice” is recognized worldwide for its distinctive ability to improve mood and relieve feelings of anxiousness in both adults and adolescents.*1-3
Because of its powerful aphrodisiac properties, saffron is used in many natural libido supplements.* But not all saffron supplements are created equal. Much of what’s sold today is loaded with other plants and artificial substances. That’s why we formulated our saffron supplement with the purest ingredients available.*

The BrainMD Promise
OUR PRODUCTS ARE SUPERIOR IN FORMULA, INGREDIENTS, TASTE AND QUALITY.
At BrainMD, we’ve dedicated our careers to helping people like you feel better with all natural, ethically sourced ingredients. Plus, they’re free of gluten, wheat, eggs, corn, sugars, artificial coloring or flavoring, and common toxins that many manufacturers don’t check for—like dioxins.
From source to shelf, we extensively test and track every bottle, ensuring that you receive the absolute best. If you aren’t 100% satisfied with our product, you’ll receive your money back.
▪OUR CEO SAYS▪
“This is my favorite product I take every day. The ingredients in Happy Saffron Plus are backed by 24 randomized control trials, but the reason I fell in love with this formula is that it supports mood, memory, and sexual function.”
- Daniel G. Amen, MD

Cutting-Edge Curcumin
Longvida® curcumin is 95x more bioavailable than standard curcumin extracts and is the only curcumin extract in the world to use cutting-edge SLCP™ Technology to increase curcumin absorption.* Shown to be the most effective curcumin on the market, Longvida® is patented for cognition and anti-aging.* And, unlike many other forms of curcumin, it can effectively cross the blood-brain barrier.*
Clinical research shows that 400 mg of Longvida® supports cognition, memory, mood, and attention while reducing stress reactivity and fatigue.*6,7 Also, the same dosage supports a 16% increase in working memory within just 1 hour of taking the first dose!*6

Get Happy (Without Side Effects!)
Zinc is an essential micronutrient crucial to more than 300 enzymatic reactions.*8,9 The body needs zinc to make energy, DNA and proteins, antioxidant enzymes, and to make new cells for immunity and healthy growth and development.*10
Results from six randomized, double-blind, placebo-controlled studies suggest supplementing with zinc can improve mood in healthy individuals and people with mood problems.*11,12
When combined with saffron and curcumin, this powerful trio of ingredients can help transform your mood and support your best health without any unwanted side effects.*

Clinically Researched Benefits
As a company firmly rooted in science, we use only clinically researched ingredients that create real results. Here are some of the benefits of taking the natural mood enhancer Happy Saffron Plus:
- Happier mood*
- Enhanced memory & cognition*
- Improved sexual function*
- Greater resilience to stress*
- Increased focus*
- Decreased feelings of anxiousness*
- Better joint health & mobility*
- More energy*
- Appetite control*
References
- Toth B, others. The efficacy of saffron in the treatment of mild to moderate depression: A meta-analysis. Planta Medica 85:24-31 (2019).
- Ghaderi A, others. Effects of saffron (Crocus sativus L.) on mental health parameters and C-reactive protein: A meta-analysis of randomized clinical trials. Complementary Therapies in Medicine 48, 102250; doi.org/10.1016/j.ctim.2019.102250 (7 pages) (2020).
- Paula Almodóvar, David Briskey, Amanda Rao, Marín Prodanov, Antonio M. Inarejos-García, "Bioaccessibility and Pharmacokinetics of a Commercial Saffron (Crocus sativus L.) Extract", Evidence-Based Complementary and Alternative Medicine, vol. 2020, Article ID 1575730, doi.org/10.1155/2020/1575730 (8 pages) (2020).
- Kell G, others. affron® a novel saffron extract (Crocus sativus L.) improves mood in healthy adults over 4 weeks in a double-blind, parallel, randomized, placebo-controlled clinical trial. Complementary Therapies in Medicine 33:58-64 (2017).
- Cox KH et al. Investigation of the effects of solid lipid curcumin on cognition and mood in a healthy older population. Centre for Human Psychopharmacology, Swinburne University. J Psychopharmacol. May 2015. (Vol 29) No 5: 642-651. DOI: 10.1177/0269881114552744
- Cox KHM, White DJ, Pipingas A, Poorun K, Scholey A. Further Evidence of Benefits to Mood and Working Memory from Lipidated Curcumin in Healthy Older People: A 12-Week, Double-Blind, Placebo-Controlled, Partial Replication Study. Nutrients. 2020 Jun 4;12(6):1678. doi: 10.3390/nu12061678. PMID: 32512782; PMCID: PMC7352411.
- Maret W. Zinc biochemistry: From a single zinc enzyme to a key element of life. Advances in Nutrition 4:82-91 (2013).
- Portbury SD, Adlard PA. Zinc signal in brain diseases. International Journal of Molecular Sciences 18, 2506; doi:10.3390/ijms18122506 (13 pages) (2017).
- NIH Office of Dietary Supplements. Zinc Fact Sheet for Health Professionals. ods.od.nih.gov (12 pages) (July 10, 2019, accessed February 24, 2020).
- Petrilli MA, others. The emerging role for zinc in depression and psychosis. Frontiers in Pharmacology 8, 414; doi: 10.3389/fphar.2017.00414 (12 pages) (2017).
- Yosaee S, others. Effects of zinc, vitamin D, and their co-supplementation on mood, serum cortisol, and brain-derived neurotrophic factor in patients with obesity and mild to moderate depressive symptoms: A phase II, 12-wk, 2x2 factorial design, double-blind, randomized, placebo-controlled trial. Nutrition 71:110601; doi: 10.1016/j.nut.2019.110601 (2020).
Frequently Asked Questions
How do l take Happy Saffron Plus?
How do l take Happy Saffron Plus?
We recommend adults take 3 capsules daily between meals.
Can children take this product?
Can children take this product?
Children ages 4-18 years can take 1 capsule per 40 pounds body weight, maximum 3 capsules daily.
Does this supplement contain allergens?
Does this supplement contain allergens?
It is free from dairy, glutens, sugar, corn, nuts, eggs, yeast, and artificial flavorings or colorings. It contains traces of soy (non-GMO).
Is Happy Saffron Plus suitable for vegans?
Is Happy Saffron Plus suitable for vegans?
Yes. BrainMD’s Happy Saffron Plus is suitable for vegans, especially those seeking to improve their mood.
Is it possible to get hooked on this product?
Is it possible to get hooked on this product?
As with other BrainMD products, this is a dietary supplement not a drug. It isn’t habit-forming.
I'm already using a different BrainMD mood product. Do l need to discontinue that productbefore taking Happy Saffron Plus?
I'm already using a different BrainMD mood product. Do l need to discontinue that productbefore taking Happy Saffron Plus?
No. Happy Saffron Plus can be used in conjunction with any of BrainMD’s mood supplements.